Kingsholm Liberal Democrats have launched a new petition to stop the area being overwhelmed by Houses in Multiple Occupation.
Family homes are being converted into properties suitable for renting and can lead to issues with noise, rubbish and parking.
There can also be problems with getting landlords to deal with incidents of anti-social behaviour.
Current planning rules do not require permission for new HMOs of less than six people.
Areas such as St Paul’s in Cheltenham have an Article 4 Direction, which requires planning permission for all new HMOs.
Liberal Democrat councillors Jeremy Hilton and Isabel Brazil recently tried in vain to persuade the Tory administration on the city council to do a housing stock survey immediately, which would be a precursor to an Article 4 designation for Kingsholm.
Councillor Isabel Brazil said: “It has been noticeable that in recent times more and more family homes in Kingsholm are being converted into Houses in Multiple Occupation.
“This is changing the nature of the community as absentee landlords buy up homes and let rooms to individuals to maximise their income.”
Councillor Jeremy Hilton added: “We are raising a petition to demand that the city council starts work right now on preparing the evidence to apply for Article 4 Direction to the Secretary of State.
“We cannot have Kingsholm overrun by HMOs, we need a fair balance.”
The petition can be signed here